Vanderbilt University 

Description: Traditional mathematical model-based anatomical models have been replaced with more realistic standardized anatomical models based on patient image data. Calculation of internal dose estimates from animal or human data sets requires knowledge of a number of important principles and relationships in kinetic analysis and dose assessment, and knowledgeable use of available software tools. This program will give an overview of standard calculation techniques and models, and demonstrate how new models have introduced changes to standard calculations, with practical examples worked out in several important areas of application. A brief discussion will be included of current issues in radiation biology that are pertinent to the interpretation of calculated dose estimates.